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Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes, genes.
Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in cancer.
As the discovery, identification, characterization and validation of novel human drug targets for anti-cancer drug discovery continues to grow; this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

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Volume 3, Number 5, October 2003

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Book review

Review article

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Overview: Translating Hsp90 Biology into Hsp90 Drugs
pp. 297-300(4)
Author: Workman, Paul

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Structure and Functional Relationships of Hsp90
pp. 301-323(23)
Authors: Prodromou, Chrisostomos; Pearl, Laurence H.

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Natural Product Origins of Hsp90 Inhibitors
pp. 325-330(6)
Author: Uehara, Yoshimasa

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Genes and Proteins Governing the Cellular Sensitivity to HSP90 Inhibitors: A Mechanistic Perspective
pp. 331-341(11)
Authors: Maloney, Alison; Clarke, Paul A.; Workman, Paul

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The Stress Response: Implications for the Clinical Development of Hsp90 Inhibitors
pp. 349-358(10)
Authors: Whitesell, Luke; Bagatell, Rochelle; Falsey, Ryan

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Development of Radicicol Analogues
pp. 359-369(11)
Authors: Soga, Shiro; Shiotsu, Yukimasa; Akinaga, Shiro; Sharma, Sreenath V.

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Development of Purine-Scaffold Small Molecule Inhibitors of Hsp90
pp. 371-376(6)
Authors: Chiosis, Gabriela; Lucas, Brian; Huezo, Henri; Solit, David; Basso, Andrea; Rosen, Neal

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Clinical Development of 17-Allylamino, 17-Demethoxygeldanamycin
pp. 377-383(7)
Authors: Sausville, Edward A.; Tomaszewski, Joseph E.; Ivy, Percy

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The Clinical Applications of Heat Shock Protein Inhibitors in Cancer - Present and Future
pp. 385-390(6)
Authors: Banerji, Udai; Judson, Ian; Workman, Paul

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