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Current Chemical Biology aims to publish full-length and mini reviews on exciting new developments at the chemistry-biology interface, covering topics relating to Chemical Synthesis, Science at Chemistry-Biology Interface and Chemical Mechanisms of Biological Systems.

Current Chemical Biology covers the following areas: Chemical Synthesis (Syntheses of biologically important macromolecules including proteins, polypeptides, oligonucleotides, oligosaccharides etc.; Asymmetric synthesis; Combinatorial synthesis; Diversity-oriented synthesis; Template-directed synthesis; Biomimetic synthesis; Solid phase biomolecular synthesis; Synthesis of small biomolecules: amino acids, peptides, lipids, carbohydrates and nucleosides; and Natural product synthesis).

Science at Chemistry-Biology Interface (Chemical informatics; Macromolecular catalysts and receptors; Enzymatic synthesis; Biosynthetic engineering; Combinatorial biosynthesis; Plant cell based chemistry; Bacterial and viral cell based chemistry; Chemistry of cellular processes in plants/animals; Receptor chemistry; Cell signaling chemistry; Drug design through understanding of disease processes; Synthetic biology; New high throughput screening techniques; Small molecular array fabrication; Chemical genomics; Chemical and biological approaches to carbohydrates proteins and nucleic acids design; Chemical and biological regulation of biosynthetic pathways; and Unnatural biomolecular analogs).

Publisher: Bentham Science Publishers

Volume 3, Number 1, January 2009

Articles

Aging and DNA Methylation
pp. 1-9(9)
Authors: Kim, Jei; Kim, Jee-Yeon; Issa, Jean-Pierre J.

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Human 90 kDa Heat Shock Protein Hsp90 as a Target for Cancer Therapeutics
pp. 10-21(12)
Authors: Gava, Lisandra M.; Ramos, Carlos H.I.

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Reactive Oxygen Species, Cancer and Anti-Cancer Therapies
pp. 22-46(25)
Authors: Manda, Gina; Nechifor, Marina T.; Neagu, Teodora-Monica

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Entropy and Enthalpy in the Activity of Tubulin-Based Antimitotic Agents
pp. 47-59(13)
Authors: Daly, Erin M.; Taylor, Richard E.

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Bioactive N-Phenylimidazole Derivatives
pp. 65-88(24)
Authors: Pastor, Isidro M.; Yus, Miguel

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Polyphyllin D - A Potential Anti-Cancer Agent to Kill Hepatocarcinoma Cells with Multi-Drug Resistance
pp. 89-99(11)
Authors: Lee, Rebecca K.Y.; Ong, Rose C.Y.; Cheung, Jenny Y.N.; Li, Yan C.; Chan, Judy Y.W.; Lee, Macey M.S.; Suen, Yick K.; Fung, Kwok P.; Ho, Ho P.; Yu, Bao; Li, Ming; Kwok, Tim T.; Kong, Siu K.

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The Use of Small Molecules to Correct Defects in CFTR Folding, Maturation, and Channel Activity
pp. 100-111(12)
Authors: Rosser, Meredith F.N.; Grove, Diane E.; Cyr, Douglas M.

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Synthesis, Characterisation, Anti-Microbial Activity and Docking Studies of Novel Dispiro- Oxindolopyrrolidines
pp. 112-123(12)
Authors: Suresh Babu, Adukamparai R.; Raghunathan, Raghavachary; Kumaresan, Kuppamuthu; Raaman, Nanjian

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