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Current Chemical Biology aims to publish full-length and mini reviews on exciting new developments at the chemistry-biology interface, covering topics relating to Chemical Synthesis, Science at Chemistry-Biology Interface and Chemical Mechanisms of Biological Systems.

Current Chemical Biology covers the following areas: Chemical Synthesis (Syntheses of biologically important macromolecules including proteins, polypeptides, oligonucleotides, oligosaccharides etc.; Asymmetric synthesis; Combinatorial synthesis; Diversity-oriented synthesis; Template-directed synthesis; Biomimetic synthesis; Solid phase biomolecular synthesis; Synthesis of small biomolecules: amino acids, peptides, lipids, carbohydrates and nucleosides; and Natural product synthesis).

Science at Chemistry-Biology Interface (Chemical informatics; Macromolecular catalysts and receptors; Enzymatic synthesis; Biosynthetic engineering; Combinatorial biosynthesis; Plant cell based chemistry; Bacterial and viral cell based chemistry; Chemistry of cellular processes in plants/animals; Receptor chemistry; Cell signaling chemistry; Drug design through understanding of disease processes; Synthetic biology; New high throughput screening techniques; Small molecular array fabrication; Chemical genomics; Chemical and biological approaches to carbohydrates proteins and nucleic acids design; Chemical and biological regulation of biosynthetic pathways; and Unnatural biomolecular analogs).

Publisher: Bentham Science Publishers

Volume 2, Number 1, January 2008

Articles

Towards the Targeted Modulation of Gene Expression by Modified Triplex-Forming Oligonucleotides
pp. 1-10(10)
Authors: Fox, Keith R.; Rusling, David A.; Broughton-Head, Victoria J.; Brown, Tom

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Inhibitors of Multisubunit RNA Polymerases as Tools to Study Transcriptional Mechanisms in Prokaryotes and Eukaryotes
pp. 20-31(12)
Authors: Coulombe, Benoit; Domecq, Celine; Trinh, Vincent; Langelier, Marie-France; Archambault, Jacques

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Trends and Challenges in Directed Evolution
pp. 50-59(10)
Authors: Bustos-Jaimes, Ismael; Montiel, Carmina

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GIP-Based Therapeutics for Diabetes and Obesity
pp. 60-67(8)
Authors: Gault, Victor A.; Irwin, Nigel; Flatt, Peter R.

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Emerging Roles for Metabolic Engineering - Understanding Primitive and Complex Metabolic Models and Their Relevance to Healthy and Diseased Kidney Podocytes
pp. 68-82(15)
Authors: Reiser, Jochen; Altintas, Mehmet M.; Ulgen, Kutlu O.; Palmer-Toy, Darryl; Shih, Vivian E.; Kompala, Dhinakar S.

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Chemical Communication: A Visit with Insects
pp. 83-96(14)
Authors: Mohanty, Smita; Ring, Joshua R.; Prusti, Rabi K.

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