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Current Alzheimer Research publishes peer-reviewed frontier review and research articles on all areas of Alzheimer's disease. This multidisciplinary journal will help in understanding the neurobiology, genetics, pathogenesis, and treatment strategies of Alzheimer's disease. The journal publishes objective reviews written by experts and leaders actively engaged in research using cellular, molecular, and animal models. The journal also covers original articles on recent research in fast emerging areas of molecular diagnostics, brain imaging, drug development and discovery, and clinical aspects of Alzheimer's disease. Manuscripts are encouraged that relate to the synergistic mechanism of Alzheimer's disease with other dementia and neurodegenerative disorders. Book reviews, meeting reports and letters-to-the-editor are also published. The journal is essential reading for researchers, educators and physicians with interest in age-related dementia and Alzheimer's disease. Current Alzheimer Research provides a comprehensive 'bird's-eye view' of the current state of Alzheimer's research for neuroscientists, clinicians, health science planners, granting, caregivers and families of this devastating disease.

Publisher: Bentham Science Publishers

Volume 5, Number 2, April 2008
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Articles

Processing of Amyloid Precursor Protein and Amyloid Peptide Neurotoxicity
pp. 92-99(8)
Authors: Nathalie, Pierrot; Jean-Noel, Octave

BACE1 Structure and Function in Health and Alzheimer's Disease
pp. 100-120(21)
Authors: Cole, Sarah L.; Vassar, Roger

Memapsin 2 (Beta-Secretase) Inhibitors: Drug Development
pp. 121-131(11)
Authors: Ghosh, Arun K.; Kumaragurubaran, Nagaswamy; Hong, Ling; Koelsh, Gerald; Tang, Jordan

The Catalytic Core of γ-Secretase: Presenilin Revisited
pp. 147-157(11)
Author: Steiner, Harald

γ-Secretase Inhibition and Modulation for Alzheimer's Disease
pp. 158-164(7)
Author: Wolfe, Michael S.

From Presenilinase to γ-Secretase, Cleave to Capacitate
pp. 172-178(7)
Author: Xia, Weiming

A Closer Look at α-Secretase
pp. 179-186(8)
Author: Postina, Rolf

Part-Time α-Secretases: The Functional Biology of ADAM 9, 10 and 17
pp. 187-201(15)
Authors: Deuss, Miriam; Reiss, Karina; Hartmann, Dieter

Regulation of βAPP and PrPc Cleavage by α-Secretase: Mechanistic and Therapeutic Perspectives
pp. 202-211(10)
Authors: Vincent, Bruno; Cisse, Moustapha A.; Sunyach, Claire; Guillot-Sestier, Marie-Victoire; Checler, Frederic

Amyloid-Degrading Enzymes as Therapeutic Targets in Alzheimer's Disease
pp. 212-224(13)
Authors: Nalivaeva, Natalia N.; Fisk, Lilia R.; Belyaev, Nikolai D.; Turner, Anthony J.

Neprilysin and Amyloid Beta Peptide Degradation
pp. 225-231(7)
Authors: Hersh, Louis B.; Rodgers, David W.

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