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Current Alzheimer Research publishes peer-reviewed frontier review and research articles on all areas of Alzheimer's disease. This multidisciplinary journal will help in understanding the neurobiology, genetics, pathogenesis, and treatment strategies of Alzheimer's disease. The journal publishes objective reviews written by experts and leaders actively engaged in research using cellular, molecular, and animal models. The journal also covers original articles on recent research in fast emerging areas of molecular diagnostics, brain imaging, drug development and discovery, and clinical aspects of Alzheimer's disease. Manuscripts are encouraged that relate to the synergistic mechanism of Alzheimer's disease with other dementia and neurodegenerative disorders. Book reviews, meeting reports and letters-to-the-editor are also published. The journal is essential reading for researchers, educators and physicians with interest in age-related dementia and Alzheimer's disease. Current Alzheimer Research provides a comprehensive 'bird's-eye view' of the current state of Alzheimer's research for neuroscientists, clinicians, health science planners, granting, caregivers and families of this devastating disease.

Publisher: Bentham Science Publishers

Volume 2, Number 2, April 2005
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Book review

Review article

Development of Novel Amyloid Imaging Agents Based Upon Thioflavin S
pp. 109-114(6)
Authors: Wei, Jingjun; Wu, Chunying; Lankin, David; Gulrati, Anil; Valyi-Nagy, Tibor; Cochran, Elizabeth; Pike, Victor W.; Kozikowski, Alan; Wang, Yanming

Towards Practical Cognitive Assessment for Detection of Early Dementia: A 30-Minute Computerized Battery Discriminates as Well as Longer Testing
pp. 117-124(8)
Authors: Doniger, Glen M.; Zucker, David M.; Schweiger, Avraham; Dwolatzky, Tzvi; Chertkow, Howard; Crystal, Howard; Simon, Ely S.

C-1073 (Mifepristone) in the Adjunctive Treatment of Alzheimer's Disease
pp. 125-129(5)
Authors: DeBattista, Charles; Belanoff, Joseph

A Potential Role of the Curry Spice Curcumin in Alzheimer's Disease
pp. 131-136(6)
Authors: Ringman, John M.; Frautschy, Sally A.; Cole, Gregory M.; Masterman, Donna L.; Cummings, Jeffrey L.

Synaptic Fatigue is More Pronounced in the APP/PS1 Transgenic Mouse Model of Alzheimer's Disease
pp. 137-140(4)
Authors: Zhang, Hong; Gong, Bing; Liu, Shumin; Fa, Mauro; Ninan, Ipe; Staniszewski, Agnieszka; Arancio, Ottavio

Functional Central Nicotinic Acetylcholine Receptor Antagonism by Systemic Administration of Tinuvin 770 (BTMPS)
pp. 141-147(7)
Authors: Graham, John H.; Papke, Roger L.; Buccafusco, Jerry J.

Neurotrophin Receptor-Based Strategies for Alzheimer's Disease
pp. 167-169(3)
Authors: Longo, Frank M.; Massa, Stephen M.

Nitric Oxide Mimetic Molecules as Therapeutic Agents in Alzheimer's Disease
pp. 171-182(12)
Authors: Thatcher, Gregory R.J.; Bennett, Brian M.; Reynolds, James N.

Small Molecule TGF-beta Mimetics as Potential Neuroprotective Factors
pp. 183-186(4)
Authors: Zhang, Hui; Zou, Kun; Tesseur, Ina; Wyss-Coray, Tony

Role of Fractalkine (CX3CL1) in Regulating Neuron-Microglia Interactions: Development of Viral-Based CX3CR1 Antagonists
pp. 187-189(3)
Authors: Streit, Wolfgang J.; Davis, Christopher N.; Harrison, Jeffrey K.

Validation of the Neuroinflammation Cycle as a Drug Discovery Target Using Integrative Chemical Biology and Lead Compound Development with an Alzheimer's Disease-Related Mouse Model
pp. 197-205(9)
Authors: Hu, Wenhui; Ranaivo, Hantamalala R.; Craft, Jeffrey M.; Van Eldik, Linda J.; Watterson, D. M.a.r.t.i.n.

Analysis of Genetic Polymorphisms in Acetylcholinesterase as Reflected in Different Populations
pp. 207-218(12)
Authors: Hasin, Yehudit; Avidan, Nili; Bercovich, Dani; Korczyn, Amos D.; Silman, Israel; Beckmann, Jacques S.; Sussman, Joel L.

Screening for Inhibitors of Tau Polymerization
pp. 219-226(8)
Authors: Pickhardt, Marcus; Bergen, Martin v.; Gazova, Zuzana; Hascher, Antje; Biernat, Jacek; Mandelkow, Eva-Maria; Mandelkow, Eckhard

Cytoskeletal Integrity as a Drug Target
pp. 227-229(3)
Authors: Michaelis, M. L.; Seyb, K. I.; Ansar, S.

Development of a High Throughput Drug Screening Assay for the Detection of Changes in Tau Levels - Proof of Concept with HSP90 inhibitors
pp. 231-238(8)
Authors: Dickey, Chad A.; Eriksen, Jason; Kamal, Adeela; Burrows, Francis; Kasibhatla, Srinivas; Eckman, Christopher B.; Hutton, Mike; Petrucelli, Leonard

Lentiviral Vector-Based Models of Amyloid Pathology: From Cells to Animals
pp. 239-247(9)
Authors: Shaughnessy, Laura; Thomas, Mary B.; Wakefield, John; Chamblin, Beth; Nair, Ayyappan; Koentgen, Frank; Ramabhadran, Ram

Pilot Study of the Reducing Effect on Amyloidosis In Vivo by Three FDA Pre-Approved Drugs Via the Alzheimer's APP 5'Untranslated Region
pp. 249-254(6)
Authors: Tucker, Stephanie; Ahl, Michelle; Bush, Ashley; Westaway, David; Huang, Xudong; Rogers, Jack T.

Drug Library Screen to Identify Compounds that Decrease Secreted Abgr from a Human Cell Line
pp. 255-259(5)
Authors: Chakrabarti, Enakshi; Smith, Jonathan D.

Recent Developments on the Studies of Human Memapsin 2 (bgr-Secretase)
pp. 261-264(4)
Authors: Tang, Jordan; He, Xiangyang; Huang, Xianping; Hong, Lin

An Abgr Sequestration Approach Using Non-Antibody Abgr Binding Agents
pp. 265-268(4)
Authors: Matsuoka, Yasuji; Shao, Li; Debnath, Manik; LaFrancois, John; Becker, Amanda; Gray, Audrey; Aisen, Paul; Mathis, Chester; Klunk, William; Duff, Karen

LRP-Mediated Clearance of Abgr is Inhibited by KPI-Containing Isoforms of APP
pp. 269-273(5)
Authors: Moir, Robert D.; Tanzi, Rudolph E.

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