Erratum

Source: Current Alzheimer Research, Volume 2, Number 1, January 2005 , pp. 103-103(1)

Publisher: Bentham Science Publishers

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Abstract:

Due to an oversight, the figure caption on the Contents page of Current Alzheimer Research, Volume 1, Number 4 was wrongly published. The corrected caption is reproduced as follows:

The figure shown on the front cover of this journal was taken from the article entitled Amyloid b-Peptide: The Inside Story (pp. 231-239) by Bertrand P. Tseng, Masashi Kitazawa and Frank M. LaFerla. The slide shows a proposed model of the effects of intraneuronal amyloid b-peptide (Ab) on key neurobiological phenomena. Ab is proteolytically derived from the large Ab precursor protein (APP). Mutations in the presenilin genes also affect the formation of intracellular Ab which exists as monomers, oligomers or fibrils. The potential pathophysiolgical contribution of intracellular Ab accumulation includes synaptic dysfunction, proteasome dysfunction, calcium dyshomeostasis and tau hyperphosphorylation. The cell membrane is shown to separate extracellular and intracellular compartments.

Document Type: Addendum

DOI: http://dx.doi.org/10.2174/1567205052772777

Publication date: 2005-01-01

More about this publication?

Current Alzheimer Research publishes peer-reviewed frontier review and research articles on all areas of Alzheimer's disease. This multidisciplinary journal will help in understanding the neurobiology, genetics, pathogenesis, and treatment strategies of Alzheimer's disease. The journal publishes objective reviews written by experts and leaders actively engaged in research using cellular, molecular, and animal models. The journal also covers original articles on recent research in fast emerging areas of molecular diagnostics, brain imaging, drug development and discovery, and clinical aspects of Alzheimer's disease. Manuscripts are encouraged that relate to the synergistic mechanism of Alzheimer's disease with other dementia and neurodegenerative disorders. Book reviews, meeting reports and letters-to-the-editor are also published. The journal is essential reading for researchers, educators and physicians with interest in age-related dementia and Alzheimer's disease. Current Alzheimer Research provides a comprehensive 'bird's-eye view' of the current state of Alzheimer's research for neuroscientists, clinicians, health science planners, granting, caregivers and families of this devastating disease.

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