Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry: A Review
Abstract:Atmospheric pressure matrix-assisted laser desorption/ionization (AP-MALDI) was first introduced in 1999. In the last few years, there has been a rapid growth in publications describing the development and application of APMALDI to the mass spectrometric analysis of peptides, polymers and oligosaccharides. This short review discusses recent advances in AP-MALDI, focusing on the analysis of biomolecules and the relative performance of MALDI at atmospheric pressure and in vacuo.
Document Type: Research Article
Affiliations: School of Biomedical and Natural Sciences, Interdisciplinary Biomedical Research Centre, Nottingham Trent University, Clifton Lane, Nottingham, NG11 8NS, UK;
Publication date: January 1, 2006
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