A New Method for a Quantitative Determination of Piroxicam in Pharmaceutical Formulations Using FT-IR Spectrometry
Abstract:A Fourier transform infrared (FT-IR) spectrometric method was developed for the rapid, and direct measurement of piroxicam (Pir) in pharmaceutical drugs. Pir is a well known and very effective antiinflammatory drug. Pir can be determined by various methods and now we are adding a new one that uses a Fourier transform infrared spectrophotometric technique. Conventional spectra were compared for best determination of active substance in pharmaceutical formulations. The Beer-Lambert law and two chemometric approaches, partial least squares (PLS) and principal component regression (PCR&plus) methods, were tried in data processing.
Document Type: Research Article
Publication date: 2012-12-01
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