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Geometric Calibration Based on Identification of Ellipse Parameters of a Micro-CT System for Small-Animal Imaging

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Micro-computed tomography (Micro-CT) is a new three-dimension high-resolution imaging device based on X-ray imaging principle. Precise assessment of the micro-CT system's geometric parameters is crucial to achieve successful reconstruction with good spatial resolution and low artifact content in the reconstructed tomography images. Noo et al. (2000) have proposed a new analytic method for calibration of X-ray cone-beam scanners that use a circular path for the cone vertex. In this paper, we use this analytic calibration method for the estimation of the geometric parameters of a practical small-animal imaging micro-CT system. We improve calibration phantom of this method in order to make it more suitable for micro-CT system. An accurate determination of system geometric parameters results from the proposed method. The projection images demonstrated that the adopt method is robust and easy to implement with high precision. The overall performance of the micro-CT system is demonstrated in some results of small-animal imaging.
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Document Type: Research Article

Publication date: 01 October 2011

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