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A Simple, Flexible, Low-Cost Acetylcholine Biosensor Based on Nano Self Assembly of Graphene

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Abstract:

The simple manufacture of the innovative and cost-effective Acetylcholine (ACh) biosensor relies on the semiconductor properties of materials such as graphene and carbon nanotubes (CNT). The connection between concentration of ACh and the respective response in conductivity is the foundation of the biosensor. The combination of self assembly technique and and a flexible polymer substrate decreases the cost of the biosensor dramatically. The detection limit of the graphene-based biosensor for ACh concentrations is as low as 1 pM with a respond time of less than 3 seconds on average, much better than a CNT based biosensor under the same conditions. This work presents a promising technique to develop low-cost and high-performance biosensors for Alzheimer disease diagnostics.

Keywords: ACETYLCHOLINE; BIOSENSOR; CARBON NANOTUBE; GRAPHENE; SELF ASSEMBLY

Document Type: Research Article

DOI: http://dx.doi.org/10.1166/sl.2011.1738

Publication date: October 1, 2011

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  • The growing interest and activity in the field of sensor technologies requires a forum for rapid dissemination of important results: Sensor Letters is that forum. Sensor Letters offers scientists, engineers and medical experts timely, peer-reviewed research on sensor science and technology of the highest quality. Sensor Letters publish original rapid communications, full papers and timely state-of-the-art reviews encompassing the fundamental and applied research on sensor science and technology in all fields of science, engineering, and medicine. Highest priority will be given to short communications reporting important new scientific and technological findings.
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