@article {Gao:2009:1546-198X:6,
title = "Detecting Penicillin in Milk with a Wireless Magnetoelastic Biosensor",
journal = "Sensor Letters",
parent_itemid = "infobike://asp/senlet",
publishercode ="asp",
year = "2009",
volume = "7",
number = "1",
publication date ="2009-02-01T00:00:00",
pages = "6-10",
itemtype = "ARTICLE",
issn = "1546-198X",
eissn = "1546-1971",
url = "https://www.ingentaconnect.com/content/asp/senlet/2009/00000007/00000001/art00002",
doi = "doi:10.1166/sl.2009.1002",
keyword = "PENICILLIN, MAGNETOELASTIC BIOSENSOR, PH",
author = "Gao, Xianjuan and Zhen, Ruiyan and Zhang, Yujun and Grimes, Craig A.",
abstract = "A wireless magnetoelastic biosensor for the direct detection of penicillin G in milk has been developed. The sensor was fabricated by applying a magnetoelastic ribbon with a layer of pH-sensitive polymer and upon it a sensing film containing bovine serum albumin (BSA) and penicillinase.
The penicillinase-catalyzed hydrolysis of penicillin G decreases the solution pH, resulting in the polymer shrinking and consequently the resonance frequency of the magnetoelastic sensor increasing. Under optimum operating conditions the system provides a wide linear response between 1.9 mM
and 5.0 mM with a very low detection limit of 1.3 mM. The immobilized penicillinase on magnetoelastic ribbon was very stable and provided good reproducible signal after regeneration up to 30 times with a relative standard deviation (R.S.D.) lower than 9%. Good recoveries and precisions were
obtained when spiked raw milk samples were analyzed.",
}