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Electron Transfer Reactivity and Catalytic Activity of Choline Oxidase in Didodecyldimethylammonium Bromide Film and Its Application for Sensitive Choline Monitoring

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Abstract:

The direct electrochemistry of choline oxidase was achieved with the help of didodecyldimethylammonium bromide. For a 0.1 M pH 7.0 phosphate buffer solution, the anodic and cathodic peaks potentials were located at –0.358 V and −0.386 V, respectively. The enzyme could also maintain its bioactivity and electrocatalyze the reduction of its substrate, choline, which might provide the possibility to develop third generation choline biosensor.

Keywords: BIOSENSOR; CHOLINE; CHOLINE OXIDASE; CYCLIC VOLTAMMETRY; ELECTRON TRANSFER; ENZYMATIC ACTIVITY

Document Type: Research Article

DOI: https://doi.org/10.1166/sl.2008.017

Publication date: 2008-02-01

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