Skip to main content

Construction of a Potentiometric Biosensor for Monitoring Urea during Peritoneal Dialysis

Buy Article:

$113.00 plus tax (Refund Policy)


A potentiometric sensor format designed for manufacturability is described. Urease was covalently attached to a commercially available pre-activated membrane. Compression of the immobilized enzyme membrane was used to reduce the thickness and recovery time of the sensor. Thermoplastic was injec- tion molded around a carbon-coated pin leaving a shallow well for deposition of an ammonium ion selective gel. Ultrasonic welding attached the immobilized enzyme membrane over the ion selective electrode. The response characteristics of the sensor were determined in flow injection and stopped-flow fluidic formats. The performance of the sensor was further demonstrated by analyzing urea in peritoneal dialysis fluid from a patient with kidney failure.


Document Type: Research Article


Publication date: 2004-09-01

More about this publication?
  • The growing interest and activity in the field of sensor technologies requires a forum for rapid dissemination of important results: Sensor Letters is that forum. Sensor Letters offers scientists, engineers and medical experts timely, peer-reviewed research on sensor science and technology of the highest quality. Sensor Letters publish original rapid communications, full papers and timely state-of-the-art reviews encompassing the fundamental and applied research on sensor science and technology in all fields of science, engineering, and medicine. Highest priority will be given to short communications reporting important new scientific and technological findings.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Terms & Conditions
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more