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Magnetic Nanoparticles and Their Potential for Contrast Enhancement in Magnetic Resonance Imaging

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Abstract:

Magnetic nanoparticles are opening new possibilities in modern medicine not only because of their material properties and sizes but especially because of their biocompatibility. The use of nanoparticles as contrast agents for magnetic resonance imaging was investigated. A better understanding of the interactions occurring between the magnetic nanoparticles and the hydrogen atom spins is needed. This can only be achieved through micromagnetic simulations, which are able to predict the behaviour of a single particle. Through the time dependent behaviour of the magnetic nanoparticles the frequency dependent characteristics including the resonance frequency are traced for various applied magnetic fields. The saturation magnetization and the resonance frequency are two important features of nanoparticles influencing the relaxation behaviour of the hydrogen spins. Magnetic nanoparticles with a large magnetic single domain state are best suited for shortening the relaxation time T 2. A multi-echo-sequence of nanoparticles with different sizes up to a multidomain state was performed to emphasize the results of the simulations.

Keywords: MAGNETIC NANOPARTICLES; MICROMAGNETISM; MRI CONTRAST ENHANCEMENT; RESONANCE; SUSCEPTIBILITY

Document Type: Research Article

DOI: http://dx.doi.org/10.1166/jsm.2012.1006

Publication date: April 1, 2012

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  • Journal of Spintronics and Magnetic Nanomaterials is an international multidisciplinary peer-reviewed journal reporting new developments in the fields of magnetic and spintronics materials including their synthesis, characterization, properties, and applications in electronics, photonics, telecommunications, computer sciences, medicine, health science, etc. JSM is the first journal devoted to the exciting field of spintronics, which is playing a fundamental role in the novel technological developments based on the new spin torque transfer phenomena.
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