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Antimicrobial Studies of Silver Nanoparticles Synthesized from Vitis vinifera Extract

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Abstract:

In our present investigation, synthesis of Silver nanoparticle (AgNP) from Vitis vinifera extract (grape) and its bactericidal potential against four pathogenic bacteria was investigated. In this study, we have developed an environment friendly technique for the green synthesis of AgNP from AgNO3 solution using Vitis vinifera extract. The nanoparticles were characterized by UV-Vis absorption spectroscopy, Dynamic Light Scattering (DLS) particle size analyser, X-ray Diffraction (XRD) and Scanning Electron Microscopy (SEM). From DLS particle size analyser and SEM image analysis, the average particle size was found to be 50 nm. The green synthesized nanoparticles were found to be highly toxic against different multidrug resistant human pathogens like Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, and Klebsiella pneumonia both in solid and liquid media.

Keywords: ANTIBACTERIAL ACTIVITY; GREEN SYNTHESIS; NANOPARTICLE CHARACTERIZATION; SILVER NANOPARTICLE; VITIS VINIFERA

Document Type: Research Article

DOI: http://dx.doi.org/10.1166/jbns.2012.1081

Publication date: December 1, 2012

More about this publication?
  • Bionanoscience attempts to harness various functions of biological macromolecules and integrate them with engineering for technological applications. It is based on a bottom-up approach and encompasses structural biology, biomacromolecular engineering, material science, and engineering, extending the horizon of material science. The journal aims at publication of (i) Letters (ii) Reviews (3) Concepts (4) Rapid communications (5) Research papers (6) Book reviews (7) Conference announcements in the interface between chemistry, physics, biology, material science, and technology. The use of biological macromolecules as sensors, biomaterials, information storage devices, biomolecular arrays, molecular machines is significantly increasing. The traditional disciplines of chemistry, physics, and biology are overlapping and coalescing with nanoscale science and technology. Currently research in this area is scattered in different journals and this journal seeks to bring them under a single umbrella to ensure highest quality peer-reviewed research for rapid dissemination in areas that are in the forefront of science and technology which is witnessing phenomenal and accelerated growth.
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