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Bioreduction and Mechanistic Aspects Involved in the Synthesis of Silver Nanoparticles Using Holarrhena antidysenterica

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An important aspect of nanobiotechnology concerns the development of biologically inspired experimental protocols. In this paper, we report biosynthesis and mechanistic aspects involved in the fabrication of silver nanoparticles (AgNPs) using leaf extract of Holarrhena antidysenterica. The plant H. antidysenterica is popularly known as kutja. It is majorly used for the treatment of diarrhoea and dysentery. In the study leaf extract of H. antidysenterica is used for the synthesis of AgNPs. Transmission Electron Microscopy (TEM) and Elemental Spectroscopy Imaging (ESI) were performed to ascertain the formation of AgNPs. The TEM study indicated AgNPs with spherical and quasispherical morphology with size range of 2 nm to 70 nm. Possible mechanism for the synthesis of AgNPs from above plant has also been proposed. The reduction of silver ions appeared to be due to the redox activities of ascorbic/dehydroascorbic acid and terpenoids while, proteins were identified as the capping agent for AgNPs. In the present study, we report fast, eco-friendly and one-step extracellular synthesis of AgNPs.
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Document Type: Research Article

Publication date: 2011-06-01

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  • Bionanoscience attempts to harness various functions of biological macromolecules and integrate them with engineering for technological applications. It is based on a bottom-up approach and encompasses structural biology, biomacromolecular engineering, material science, and engineering, extending the horizon of material science. The journal aims at publication of (i) Letters (ii) Reviews (3) Concepts (4) Rapid communications (5) Research papers (6) Book reviews (7) Conference announcements in the interface between chemistry, physics, biology, material science, and technology. The use of biological macromolecules as sensors, biomaterials, information storage devices, biomolecular arrays, molecular machines is significantly increasing. The traditional disciplines of chemistry, physics, and biology are overlapping and coalescing with nanoscale science and technology. Currently research in this area is scattered in different journals and this journal seeks to bring them under a single umbrella to ensure highest quality peer-reviewed research for rapid dissemination in areas that are in the forefront of science and technology which is witnessing phenomenal and accelerated growth.
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