Fabrication of Non-Enzymatic Biosensor Based on Metallic Catalyst-TiO2 Hollow Sphere Nanocomposite for Determining Biomolecules

$113.00 plus tax (Refund Policy)

Buy Article:


A PtRu@Tio2-hollow nanocomposite for the detection of biomolecules was synthesized by chemical reduction. First, poly(styrene-co-vinylphenylboronic acid), PSB, was prepared as a template (∼250 nm) by surfactant-free emulsion polymerization. Second, PSB/Tio2 core–shell spheres were prepared by sol–gel reaction. Finally, Tio2 hollow spheres (Tio2–H) were then formed after removing the PSB template by calcination at 450 °C under air atmosphere. To prepare the electrocatalyst, PtRu nanoparticles (NPs) were deposited onto the Tio2–H surface by chemical reduction. The prepared PtRu@Tio2–H nanocomposite was characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), and elemental analysis. A non-enzymatic sensor was fabricated by depositing the as-prepared PtRu@Tio2–H nanocomposite on the surface of a glassy carbon electrode (GCE), which was prepared by a hand casting method with Nafion solution as a binder. The sensor was tested as a biomolecule sensor, especially for the detection of glucose and dopamine. The cyclic voltammograms (CV) obtained during the oxidation studies revealed that the PtRu@Tio2–H nanocomposite showed better catalytic function toward the oxidation of dopamine. The sensing range of the non-enzymatic sensor for glucose was 5.0–100 mM in a phosphate buffer. The results demonstrated the potential usefulness of this bimetallic@Tio2–H bifunctional catalyst for biosensor applications.

Document Type: Research Article

DOI: http://dx.doi.org/10.1166/jnn.2012.6305

Publication date: July 1, 2012

More about this publication?
  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Terms & Conditions
  • ingentaconnect is not responsible for the content or availability of external websites
Related content



Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more