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Electrocatalysis for the Oxidation of NADH Based on β-Cyclodextrin/Multi-Walled Carbon Nanotubes Modified ITO Electrode

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In this study, the new nanocomposites of β-cyclodextrin (β-CD) and multi-walled carbon nanotubes (MWNTs) have been prepared and deposited on the indium tin oxide (ITO) electrodes to form the β-CD/MWNTs modified ITO electrodes. These novel modified electrodes exhibited the abilities to lower the electrooxidation potentials of NADH substantially (ca. 600 mV) in comparison with bare ITO electrodes. Furthermore, a linear response to NADH in the concentration range of 4.0 × 10−6 to 3.2 × 10−3 mol/L was observed, with a detection limit of 8.0 × 10−7 mol/L. Such ability of the novel nanocomposites to promote the electron-transfer reaction of NADH suggests great promise for dehydrogenase-based amperometric biosensors.

Document Type: Research Article


Publication date: March 1, 2012

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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