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Fabrication of Triple-Layered Magnetite-Hydrogel-Gold Nanocomposites for Biomedical Applications

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Magnetite-hydrogel-gold nanocomposites with optical-active, thermo-responsive, and magnetism have been prepared by the following consecutive steps. Hydrogel-encapsulated magnetites were first synthesized by the combination of sol–gel reaction and radical polymerization process, and the resulting magnetic hydrogels were subsequently bound with nano-sized Au (1∼3 nm) via a molecular linkage of diamine ligand which was covalently bonded to the carboxylic groups on the hydrogel surface. Au seeds anchored on the magnetic hydrogels were further reduced into nano-scale Au layer which induced the distinct red-shift of absorption band into NIR region. The optical properties and surface morphology of the nanocomposites were characterized by UV-vis spectroscopy, scanning electron microscopy (SEM), and transmission electron microscopy (TEM).
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Keywords: DIAMINE; GOLD; HYDROGEL; MAGNETITE; NANOSHELL

Document Type: Research Article

Publication date: 2012-02-01

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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