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Bioactivity Study of the Titanium Plates Treated with Microarc Oxidation and Alkali

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Microarc oxidation (MAO) and alkali treatment was used to modify the surface of titanium, which prepared different microstructure and nanostructure TiO2-based coating on titanium. The samples were analyzed by scanning electron microscopy (SEM), atomic force microscopy (AFM), X-ray diffraction (XRD), and contact angle measuring instrument. The sample's surface treated by MAO process was microporous structure and looks like a crate. In vitro bioactivity experiment indicated that the hydroxyapatite precipitates was as squama and grew perpendicularly on the sample's surface. In vitro cell culture and MTT assay the MAO-NaOH samples showed distinct proliferation levels compared to the MAO samples. It has no toxicity to the growth of MSC cell and had better biocompatibility. According to the calculation of surface energy, that better hydrophilicity of materials will induce the more growth of hydroxyapatite.


Document Type: Research Article


Publication date: 2011-11-01

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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