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Labeling Primary Nerve Stem Cells with Quantum Dots

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Abstract:

The primary nerve stem cells (NSCs) were labeled with the carboxyl QDs by passive loading. The studies on QDs' effect on the NSCs showed that with a proper concentration, QDs have little effect on NSCs growth and proliferation within a week, and the QDs did not affect either differentiation potential of NSCs or the protein expression of neuron and astrocyte derived from NSCs. The results suggested that this labeling method is appropriate for labeling studies in vitro. Combined with the unique optical properties of QDs, it is possibly to fulfill NSCs fate-tracking in vivo.

Keywords: LABELING; NERVE STEM CELL; PASSIVE LOADING; QUANTUM DOTS

Document Type: Research Article

DOI: http://dx.doi.org/10.1166/jnn.2011.5322

Publication date: November 1, 2011

More about this publication?
  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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