Preparation and Characterization of Poly(vinyl alcohol)/Poly(-caprolactone)-Poly(ethylene glycol)-Poly(-caprolactone)/Nano-Hydroxyapatite Composite Membranes for Tissue Engineering
Abstract:In this paper, the poly(vinyl alcohol)/poly(-caprolactone)-PEG-poly(-caprolactone)/nano-hydroxyapatite (PVA/PCEC/n-HA) composite membranes were prepared by solution casting and evaporation methods. The effect of n-HA content on the properties of the composite membranes was studied. The PVA/PCEC/n-HA composite membranes were analyzed by FTIR spectroscopy, X-ray diffraction, water content measurement, contact angle, mechanical test, scanning electron microscopy. The results showed that the surface roughness of the composite membranes increased with the increase of n-HA contents. The n-HA content had obvious influence on the swelling ratio, tensile strength and elongation rate of the composite membranes. With the increase of n-HA contents, the swelling ratio increased at first, and then decreased; tensile strength and elongation rate decreased gradually. The PVA/PCEC/n-HA composite membranes may be applied in the field of tissue engineering.
Document Type: Research Article
Publication date: March 1, 2011
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