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Preparation and Characterization of Poly(vinyl alcohol)/Poly(-caprolactone)-Poly(ethylene glycol)-Poly(-caprolactone)/Nano-Hydroxyapatite Composite Membranes for Tissue Engineering

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Abstract:

In this paper, the poly(vinyl alcohol)/poly(-caprolactone)-PEG-poly(-caprolactone)/nano-hydroxyapatite (PVA/PCEC/n-HA) composite membranes were prepared by solution casting and evaporation methods. The effect of n-HA content on the properties of the composite membranes was studied. The PVA/PCEC/n-HA composite membranes were analyzed by FTIR spectroscopy, X-ray diffraction, water content measurement, contact angle, mechanical test, scanning electron microscopy. The results showed that the surface roughness of the composite membranes increased with the increase of n-HA contents. The n-HA content had obvious influence on the swelling ratio, tensile strength and elongation rate of the composite membranes. With the increase of n-HA contents, the swelling ratio increased at first, and then decreased; tensile strength and elongation rate decreased gradually. The PVA/PCEC/n-HA composite membranes may be applied in the field of tissue engineering.

Keywords: MEMBRANE; NANO-HYDROXYAPATITE; POLY(EPSI-CAPROLACTONE)-POLY(ETHYLENE GLYCOL)-POLY(EPSI-CAPROLACTONE); POLY(VINYL ALCOHOL); TISSUE ENGINEERING

Document Type: Research Article

DOI: http://dx.doi.org/10.1166/jnn.2011.3139

Publication date: March 1, 2011

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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