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A Ferrofluid Guided System for the Rapid Separation of the Non-Magnetic Particles in a Microfluidic Device

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Abstract:

A microfluidic device was fabricated via UV lithography technique to separate non-magnetic fluoresbrite carboxy microspheres (∼4.5 μm) in the pH 7 ferrofluids made of magnetite nanoparticles (∼10 nm). A mixture of microspheres and ferrofluid was injected to a lithographically developed Y shape microfluidic device, and then by applying the external magnet fields (0.45 T), the microspheres were clearly separated into different channels because of the magnetic force acting on those non-magnetic particles. During this study, various pumping speeds and particle concentrations associated with the various distances between the magnet and the microfluidic device were investigated for an efficient separation. This study may be useful for the separation of biological particles, which are very sensitive to pH value of the solutions.

Keywords: EXTERNAL MAGNETIC FIELD; FERROFLUID; MICROFLUIDIC DEVICE; SEPARATION OF NON-MAGNETIC PARTICLES

Document Type: Research Article

DOI: https://doi.org/10.1166/jnn.2010.2643

Publication date: 2010-10-01

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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