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Biotinylated Lipid Membrane Patterns Supported by Proteins for the Recognition of Streptavidined Polystyrene Microspheres

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Abstract:

Human serum albumin (HSA) patterns constructed on glass substrate by the micro-contact printing (CP) technique are fabricated to support phospholipids membranes functionalized with biotinylated lipid. The experiment results indicate that this kind of lipid membrane has been assembled on HSA patterns with good stability. And the streptavidin-coated PS microspheres can be deposited on such lipid patterns with high efficiency. In this way, it may create a route to change the biological interface in the fabrication of biosensor.

Keywords: LIPID MEMBRANE; MOLECULAR RECOGNITION; PATTERN; SURFACE MODIFICATION

Document Type: Research Article

DOI: http://dx.doi.org/10.1166/jnn.2010.2527

Publication date: October 1, 2010

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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