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Multi-Amine-Grafted SBA-15 Spherical Nanoparticles for the Adsorption of Proteins

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Abstract:

Mesoporous silica spheres (SBA-15) have been obtained via a two-step synthesis process by using a triblock copolymer as a template in combination with a co-surfactant and co-solvent. Multi-amine-grafted mesoporous silicas were prepared by attaching 3-aminopropyl triethoxysilane, N-2(-aminoethyl)-3-aminopropyltrimethoxysilane and (3-trimethoxysilylpropyl)diethylenetriamine via a post-synthetic method. The proteins used in adsorption experiments include Bovine Serum Albumin (BSA), Lysozyme (LYS) and Myoglobin (MYO). The protein adsorption properties such as equilibrium and kinetics were investigated. The results show that the original SBA-15 samples have the highest adsorption capacity for all proteins due to their largest pore size and internal surface area.

Keywords: ADSORPTION; MESOPOROUS MATERIAL; PROTEINS; SBA-15; SPHERE

Document Type: Research Article

DOI: https://doi.org/10.1166/jnn.2010.2323

Publication date: 2010-05-01

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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