@article {Jere:2010:1533-4880:3366,
title = "Biodegradable Nano-Polymeric System for Efficient Akt1 siRNA Delivery",
journal = "Journal of Nanoscience and Nanotechnology",
parent_itemid = "infobike://asp/jnn",
publishercode ="asp",
year = "2010",
volume = "10",
number = "5",
publication date ="2010-05-01T00:00:00",
pages = "3366-3369",
itemtype = "ARTICLE",
issn = "1533-4880",
eissn = "1533-4899",
url = "https://www.ingentaconnect.com/content/asp/jnn/2010/00000010/00000005/art00074",
doi = "doi:10.1166/jnn.2010.2228",
keyword = "SIRNA DELIVERY, AKT1 PROTEIN, LUNG CANCER, GENE DELIVERY, NONVIRAL VECTORS, POLYMERIC CARRIER, POLYCAPROLACTONE, NANOCARRIERS",
author = "Jere, Dhananjay and Arote, Rohidas and Jiang, Hu-Lin and Kim, You-Kyoung and Cho, Myung-Haing and Cho, Chong-Su",
abstract = "Biodegradable nano-polymeric carrier composed of polycaprolactone (PCL) and polyethylenimine (PEI) (BNPP) was successfully synthesized for the delivery of sh/siRNA in lung cancer cells. BNPP efficiently and safely delivered siRNA in lung cancer cells. BNPP-delivered Akt1 siRNA silenced Akt1 protein, and reduced the cancer cell survival, proliferation, malignancy and metastasis.",
}