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Preparation of Photocontrollable, Nontoxicity Complex of Phenylazophenylalanine Modified CdS Quantum Dots with Cyclodextrin

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Abstract:

A novel complex of β-cyclodextrin with phenylazophenylalanine (PAP)-conjugated CdS quantum dot (Fazo-CdS QD) was fabricated for a photocontrollable toxicity study of CdS. Photocontrolling release of Fazo-CdS QDs from the complex was confirmed under UV irradiation by the steady state photoluminescence (PL) spectroscopy. The cytotoxicity of the surface modified CdS QDs was evaluated in vivo. The results suggest that the Fazo-CdS QDs conjugated with β-CD could be almost nontoxicity, which may have great potential applications in biological labeling and imaging.

Keywords: BETA-CYCLODEXTRIN; CYTOTOXICITY; PHENYLAZOPHENYLALANINE; PHOTOCONTROLLABLE RELEASE; QUANTUM DOTS

Document Type: Research Article

DOI: http://dx.doi.org/10.1166/jnn.2010.1723

Publication date: January 1, 2010

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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