@article {Choi:2009:1533-4880:6483, title = "Detection of Neural Signals with Vertically Grown Single Platinum Nanowire-Nanobud", journal = "Journal of Nanoscience and Nanotechnology", parent_itemid = "infobike://asp/jnn", publishercode ="asp", year = "2009", volume = "9", number = "11", publication date ="2009-11-01T00:00:00", pages = "6483-6486", itemtype = "ARTICLE", issn = "1533-4880", eissn = "1533-4899", url = "https://www.ingentaconnect.com/content/asp/jnn/2009/00000009/00000011/art00033", doi = "doi:10.1166/jnn.2009.1462", keyword = "NANOWIRE, FOCUSED ION BEAM, NEURON PROBE", author = "Choi, D. S. and Fung, A. O. and Moon, H. and Villareal, G. and Chen, Y. and Ho, D. and Presser, N. and Stupian, G. and Leung, M.", abstract = "We developed a nanoscale neural probing device for in vitro sensing of neural activity. Single vertical platinum (Pt) nanowires were fabricated on a microelectrode array by focused ion beam (FIB)-chemical vapor deposition (CVD) in order to improve the spatial resolution of recording and to minimize damage to the cells. Rat neuroblasts were cultured on the electrode array. Electrodes in contact with cells detected prominent spontaneous electrical activity. Our experiments demonstrate the nanoprobes for the real-time detection of electrophysiological signals in neuronal cells.", }