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Preparation of Biopolymer-Coated Magnetite Nanoparticles for Magnetic Resonance Image Contrast Agent

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The magnetite nanoparticles were synthesized using the sonochemical method with oleic acid as surfactant. The average size of the magnetite particles can be controlled by the ratio R = [H2O]/[surfactant] in the range of 2 to 9 nm. The size of the magnetite nanoparticles prepared by this method shows the narrow distribution. To prepare biopolymer(β-glucan)-coated magnetite nanoparticles, β-glucan solution was added to the magnetic colloid suspensions under the ultrasonication at room temperature. The β-glucan coated magnetite colloidal suspensions of various concentrations did not agglomerate for 15 days, indicating their good stability. The β-glucan-coated magnetite colloidal suspensions exhibited the enhancement of MRI contrasts in vitro.


Document Type: Research Article


Publication date: 2009-02-01

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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