DNA-Directed Self-Assembly of Fluorescent Dye-Labeled Streptavidin Arrays for Protein Detection
Abstract:In this work, a DNA lattice was utilized to direct protein self-assembly. A model biosensor system was fabricated by self-assembly of rhodamine dye-labeled streptavidin molecules on a two-tile DNA system. This self-assembly nanofabrication technique has numerous possible biotechnology applications, including use in multiplex biosensing systems that have binding of several biological molecules encoded in a multiple-tile DNA lattice.
Document Type: Short Communication
Publication date: November 1, 2008
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