Adsorption Properties of Proteins on SBA-15 Nanoparticles Functionalized with Aminosilanes

Authors: Lee, Jae-Wook; Tra, Pham Thi; Kim, Sul-Il; Roh, Sung-Hee

Source: Journal of Nanoscience and Nanotechnology, Volume 8, Number 10, October 2008 , pp. 5152-5157(6)

Publisher: American Scientific Publishers

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Abstract:

Since the discovery of ordered mesoporous silica M41S in 1992, a variety of ordered mesoporous materials have been synthesized by using the template technique. In this work, aminosilane-modified SBA-15 nanoparticles were prepared by incorporating various aminosilanes on original SBA-15 via post synthesis method. These aminosilanes were 3-aminopropyltriethoxysilane, N-2(-aminoethyl)-3-aminopropyl trimethoxysilane and (3-trimethoxysilylpropyl)diethylenetriamine. The synthesized nanoparticles were characterized by XRD, SEM, TEM and FT-IR. Adsorption and release studies of bovine serum albumin (BSA), lysozyme and myoglobin on SBA-15 samples were investigated. It was found that the synthesized SBA-15 nanoparticles can be successfully applied in drug delivery system.

Keywords: ADSORPTION; AMINOSILANES; MESOPOROUS SBA-15; SYNTHESIS

Document Type: Research Article

DOI: http://dx.doi.org/10.1166/jnn.2008.1206

Publication date: October 1, 2008

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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