Skip to main content

Novel Telomeric Repeat Elongation Assay Performed on Zinc Oxide Nanorod Array Supports

Buy Article:

$105.00 plus tax (Refund Policy)

We developed a highly sensitive and effective telomeric repeat elongation (TRE) assay by exploiting the fluorescence signal enhancing ability of ZnO nanorod (NR) platforms. We report that this novel ZnO NR-based TRE assay can be successfully used for detecting active telomerase. Our TRE assays enable complex biological reactions between many different biological components to take place effectively on various ZnO NR platforms. Therefore, ZnO NRs can effectively determine telomerase activity even at ultratrace concentration level, by functioning as excellent fluorescence enhancing biosupports. We also show the potential of ZnO NR-based TRE assays in a high-throughput and multiplexed screening of active telomerase in a large number of samples. As telomerase is a useful biomarker in cancer diagnosis and screening, our ZnO NR-based TRE assays may prove to be not only useful in basic biological research but also in clinical testing.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Data/Media
No Metrics


Document Type: Short Communication

Publication date: 2008-01-01

More about this publication?
  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Terms & Conditions
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more