Magnetic Nanoparticles for Intracranial Thermotherapy
Authors: Jordan, Andreas; Maier-Hauff, Klaus
Source: Journal of Nanoscience and Nanotechnology, Volume 7, Number 12, December 2007 , pp. 4604-4606(3)
Publisher: American Scientific Publishers
Abstract:Thermotherapy using magnetic nanoparticles, also termed nanotherapy, is a new therapeutic concept in which tumor cells are damaged via local heat application. The principle of this method is direct injection of a magnetic fluid into a tumor and its subsequent heating in an alternating magnetic field. The heat created this way (thermotherapy) causes either direct damage to the tumor cells (depending on temperature and reaction time) or make cells more susceptible to accompanying radio- or chemotherapy. The results of a feasibility trial (phase I) on the treatment of brain tumors (glioblastoma multiforme) are presented.
Document Type: Research Article
Publication date: December 2007
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