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Collagen Coating on Hydroxyapatite Surfaces Modified with Organosilane by Chemical Vapor Deposition Method

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Abstract:

Type I collagen was coated onto the modified surfaces of hydroxyapatite (HAp) sintered body. The interfacial interaction between collagen and HAp in a nano-region was controlled by depositing the organosilane of n-octadecyltrimethoxysilane (ODS: –CH3) or aminopropyltriethoxysilane (APTS: –NH2) with a chemical vapor deposition method. The surfaces were elaborated by X-ray photoelectron spectroscopy, -potential, and contact angle measurements; the Si and/or N peaks were detected, and the contact angles and surface energies were apparently different on the modified surfaces. The morphologies of collagen adsorbed on the surfaces of HAp and HAp deposited with APTS were similar, however that of the surface with ODS was apparently different, due to the hydrophobic interaction between the organic head group of –CH3 and residual groups of collagen.

Keywords: CHEMICAL VAPOR DEPOSITION (CVD) METHOD; COLLAGEN; HYDROXYAPATITE SINTERED BODY; ORGANOSILANE

Document Type: Research Article

DOI: https://doi.org/10.1166/jnn.2007.524

Publication date: 2007-03-01

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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