Carbon Nanotube-Templated Assembly of Protein
Authors: Liu, Guodong; Lin, Yuehe
Source: Journal of Nanoscience and Nanotechnology, Volume 6, Number 4, April 2006 , pp. 948-953(6)
Publisher: American Scientific Publishers
Abstract:
This paper describes a novel general strategy for fabricating protein-polyion multilayers by electrostatic layer-by-layer (LBL) self-assembly on carbon nanotube templates. Such a noncovalent functionalization method is important for preserving the activity of biomolecular, the mechanical, and electrical properties of carbon nanotubes. Glucose oxidase and poly(diallyldimethylammonium) chloride polymer (PDDA) were used as models to investigate the LBL process on CNT templates. High-resolution TEM and electrochemical characterization confirm the formation of LBL nanostructures on carboxyl functionalized carbon nanotubes. We have also demonstrated the applications of these nanoshell bioreactors to direct electrochemistry of protein and biosensing. This strategy can be applied to assemble other biological molecules such as antibody, antigen, and DNA for wide bioassay applications.Keywords: CARBON NANOTUBE; TEMPLATE; LAYER-BY-LAYER SELF-ASSEMBLY; PROTEINS; BIOSENSORS
Document Type: Research article
DOI: http://dx.doi.org/10.1166/jnn.2006.133
Publication date: 2006-04-01
- Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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