@article {Rueda:2005:1533-4880:1990, title = "Single Molecule Fluorescence Control for Nanotechnology", journal = "Journal of Nanoscience and Nanotechnology", parent_itemid = "infobike://asp/jnn", publishercode ="asp", year = "2005", volume = "5", number = "12", publication date ="2005-12-01T00:00:00", pages = "1990-2000", itemtype = "ARTICLE", issn = "1533-4880", eissn = "1533-4899", url = "https://www.ingentaconnect.com/content/asp/jnn/2005/00000005/00000012/art00006", doi = "doi:10.1166/jnn.2005.505", keyword = "FLUORESCENCE RESONANCE ENERGY TRANSFER, FLUORESCENCE MICROSCOPY, NUCLEIC ACID NANOSCIENCE, CONFORMATIONAL CHANGE, FRET", author = "Rueda, David and Walter, Nils G.", abstract = "Nanoscience and nanotechnology are providing fresh approaches to engineer materials with practical applications such as molecular-sized therapeutic and diagnostic devices, drug delivery vehicles, environmental sensors, high-rate manufacturing platforms, and self-assembling nanomachines. In many cases, researchers are mimicking biological systems that easily achieve molecular scale control through directed self-assembly. In parallel, a revolution has occurred in the basic sciences, which utilizes recent advances in fluorescence microscopy to achieve single molecule detection capability. The future will see a merger of these two separate research thrusts, as single molecule detection will afford optimal control over the assembly and performance of individual nanoscale devices.", }