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Synthesis, Characterization, and Antitumoral Activity of Polyoxometalate Loaded Starch Nanocomplexes

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Using a reverse-phase microemulsion polymerization method and an encapsulating method, polyoxometalates (POMs) K6SiW11TiO40 incorporating starch microspheres have been prepared and structurally characterized by elemental analyses, IR, UV-vis, and NMR spectroscopy. The size of SiW11TiO40/starch particles is about 40–60 nm. The polyoxometalate encapsulated by a starch microsphere retains the parent structure. The starch microsphere is a good carrier, as it is able to enhance the antitumoral activity of POMs and decrease the toxicity of POMs as well.
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Keywords: ANTITUMORAL ACTIVITY; NANOCOMPLEXES; POLYOXOMETALATES; SYNTHESIS

Document Type: Research Article

Publication date: 2005-06-01

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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