Synthesis, Characterization, and Antitumoral Activity of Polyoxometalate Loaded Starch Nanocomplexes

Authors: Wang, Xiaohong; Xu, Linlin; Li, Yingwei; Li, Feng

Source: Journal of Nanoscience and Nanotechnology, Volume 5, Number 6, June 2005 , pp. 905-908(4)

Publisher: American Scientific Publishers

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Abstract:

Using a reverse-phase microemulsion polymerization method and an encapsulating method, polyoxometalates (POMs) K₆SiW₁₁TiO₄₀ incorporating starch microspheres have been prepared and structurally characterized by elemental analyses, IR, UV-vis, and NMR spectroscopy. The size of SiW₁₁TiO₄₀/starch particles is about 40–60 nm. The polyoxometalate encapsulated by a starch microsphere retains the parent structure. The starch microsphere is a good carrier, as it is able to enhance the antitumoral activity of POMs and decrease the toxicity of POMs as well.

Keywords: POLYOXOMETALATES; NANOCOMPLEXES; SYNTHESIS; ANTITUMORAL ACTIVITY

Document Type: Research article

DOI: 10.1166/jnn.2005.145

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