Authors: Haifang Wang; Jing Wang; Xiaoyong Deng; Hongfang Sun; Zujin Shi; Zhennan Gu; Yuanfang Liu; Yuliang Zhaoc

Source: Journal of Nanoscience and Nanotechnology, Volume 4, Number 8, November 2004 , pp. 1019-1024(6)

Publisher: American Scientific Publishers

Abstract:

Carbon nanotubes are promising for use in biomedical and pharmaceutical sciences. Therefore, it becomes imperative to know the basic biological properties of carbon nanotubes in vivo. We labeled the water-soluble hydroxylated carbon single-wall nanotubes with radioactive ¹²⁵I atoms, and then the tracer was used to study the distribution of hydroxylated carbon single-wall nanotubes in mice. They moved easily among the compartments and tissues of the body, behaving as small active molecules though their apparent mean molecular weight is tremendously large. This study, for the first time, affords a quantitative analysis of carbon nanotubes accumulated in animal tissues.

Keywords: CARBON SINGLE-WALL NANOTUBES; WATER-SOLUBLE; 125 I-LABELING; DISTRIBUTION; IN VIVO

Document Type: Research article

DOI: http://dx.doi.org/10.1166/jnn.2004.146

Publication date: 2004-11-01

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• Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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