Methods for Labeling Quantum Dots to Biomolecules

Authors: Zhangbi Lin; Xingguang Su; Ying Mu; Qinhan Jina

Source: Journal of Nanoscience and Nanotechnology, Volume 4, Number 6, July 2004 , pp. 641-645(5)

Publisher: American Scientific Publishers

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Abstract:

Semiconductor quantum dots (QDs) are thought to be the most promising fluorescent probe for biological and biomedical applications because of their unique size-dependent optical and electronic properties. QD bioconjugates provide important advantages over conventional organic dyes. This review compares the optical properties of nanoparticles and dyes and describes the surface modification of the QDs and the methods for biomolecules conjugating to QDs. In addition, the effect of QDs on normal physiology in real biological applications is discussed.

Keywords: QUANTUM DOTS; LABELING METHOD; BIOMOLECULES

Document Type: Research article

DOI: http://dx.doi.org/10.1166/jnn.2004.001

Publication date: 2004-07-01

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Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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