Nanoscale Analysis of Biofunctional Molecules and Components

Authors: W. Metzger; M. Oberringer; J. Hu; M.Q. Li; U. Hartmann

Source: Journal of Nanoscience and Nanotechnology, Volume 4, Number 5, October 2004 , pp. 489-495(7)

Publisher: American Scientific Publishers

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Abstract:

In basic medical research, as well as in concrete clinical applications, the nanoscale analysis of biofunctional units is of strongly increasing relevance. Dedicated investigations on molecules, molecular composites or functional units can efficiently be performed ex or in situ by scanning probe methods and, namely, by scanning force microscopy. In the following investigations, the folding behavior of DNA is presented as an example of basic research in medicine. In contrast, the investigation of bioadsorption phenomena in systems on which apheresis therapies are based provides a real contribution to applied medicine.

Keywords: DNA; NANOSTRUCTURE; NANOLITHOGRAPHY; COATINGS; HEMOCOMPATIBILITY; FIBRINOGEN; APHERESIS

Document Type: Review article

DOI: http://dx.doi.org/10.1166/jnn.2004.076

Publication date: 2004-10-01

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Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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