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Investigation of the Stochastic Dynamics of Kinesin Nanomotor Protein: Effect of Average Potential Value

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Abstract:

We study the role of the average potential value in the stochastic dynamics of molecular nanomotors like kinesin based on Langevin equations in the presence of thermal noise. We consider the intracellular motion of the nanomotor based on different types of bistable potentials with two and three separate minima, symmetrically and asymmetrically. In the present work, Laser distribution as a comprehensive distribution is considered for the stationary probability density. The effects of the parmeters of the Laser distribution on the stationary probability density and the mean current are investigated. Some properties of the mean current of the nanomotors like the dependency of the current on the noise intensity, and the equilibrium distance for various values of average potential using the different types of bistable potentials is studied.

Keywords: ASYMMETRIC POTENTIALS; LANGEVIN DYNAMICS; MODELING NANOMOTOR MOTION; NOISE INTENSITY; STATIONARY PROBABILITY DENSITY

Document Type: Research Article

DOI: http://dx.doi.org/10.1166/jctn.2010.1628

Publication date: November 1, 2010

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  • Journal of Computational and Theoretical Nanoscience is an international peer-reviewed journal with a wide-ranging coverage, consolidates research activities in all aspects of computational and theoretical nanoscience into a single reference source. This journal offers scientists and engineers peer-reviewed research papers in all aspects of computational and theoretical nanoscience and nanotechnology in chemistry, physics, materials science, engineering and biology to publish original full papers and timely state-of-the-art reviews and short communications encompassing the fundamental and applied research.
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