If you are experiencing problems downloading PDF or HTML fulltext, our helpdesk recommend clearing your browser cache and trying again. If you need help in clearing your cache, please click here . Still need help? Email help@ingentaconnect.com

Mesoscopic Spatiotemporal Dynamics of Linear and Rotary Molecular Motors

$113.00 plus tax (Refund Policy)

Buy Article:

Abstract:

We present theoretical models and discuss the computational modelling of complex linear and rotary molecular motor systems. The computer modelling of the linear motor systems is based on spatially and temporally resolved Fokker-Planck equations. These describe the coupled dynamics of molecular motors that are bound to filaments and molecular motors that diffuse freely in the embedding medium. Our modelling of the rotary molecular motor systems is based on spatially and temporally resolved extended Navier-Stokes equations describing the mutual influence of motor rotation and fluid dynamics as well as spatial inhomogeneities. Our models consider space dependent propagation and rotation of motors, a spatially inhomogeneous motor distribution and spatial fluctuations in molecular properties. The simulations reveal the importance of systems biology on a mesoscopic scale that determines the behaviour of complex bimotor systems: Depending on the initial molecular distribution, motor-environment coupling, and spatio-temporal disorder, a spatially well-ordered organization or a controlled motion may result.

Keywords: MOLECULAR MOTORS; SPACE-TIME MODELLING; SPATIO-TEMPORAL DYNAMICS

Document Type: Research Article

DOI: http://dx.doi.org/10.1166/jctn.2006.009

Publication date: December 1, 2006

More about this publication?
  • Journal of Computational and Theoretical Nanoscience is an international peer-reviewed journal with a wide-ranging coverage, consolidates research activities in all aspects of computational and theoretical nanoscience into a single reference source. This journal offers scientists and engineers peer-reviewed research papers in all aspects of computational and theoretical nanoscience and nanotechnology in chemistry, physics, materials science, engineering and biology to publish original full papers and timely state-of-the-art reviews and short communications encompassing the fundamental and applied research.
  • Editorial Board
  • Information for Authors
  • Submit a Paper
  • Subscribe to this Title
  • Terms & Conditions
  • ingentaconnect is not responsible for the content or availability of external websites
Related content

Tools

Favourites

Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more