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Biophysical Implications of the Peyrard-BishopDauxois Model of DNA Dynamics

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In this paper, we expand and elaborate on one of the most widely used nonlinear models of DNA dynamics. A part of this work is dedicated to the parameter of helical interaction within this simple, but not trivial model of a DNA molecule. We also propose an interesting role for the so-called breather solitons emerging from the model and being involved in protein regulation of nonlinear dynamics of DNA. Finally, we examine the possible role of harmonic electric fields in the unzipping of complementary strands of DNA.
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Keywords: BREATHER MODES; DNA; PBD MODEL; REGULATORY PROTEINS

Document Type: Research Article

Publication date: 2004-09-01

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  • Journal of Computational and Theoretical Nanoscience is an international peer-reviewed journal with a wide-ranging coverage, consolidates research activities in all aspects of computational and theoretical nanoscience into a single reference source. This journal offers scientists and engineers peer-reviewed research papers in all aspects of computational and theoretical nanoscience and nanotechnology in chemistry, physics, materials science, engineering and biology to publish original full papers and timely state-of-the-art reviews and short communications encompassing the fundamental and applied research.
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