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With the aim at formulating new materials with biocidal activity a silver/polyurethane nanocomposite was prepared by in situ reduction of silver nitrate in a solution consisting of a commercial poly(carbonate urethane) dissolved in DMF, DMF acting as both polymer solvent and
reducing agent. Bacteriological tests were performed with mesophilic, Gram-positive and Gram-negative bacteria, in liquid media and on solid agar plates supplemented with nanocomposite film samples. The growth inhibition achieved proved that the material set up was an effective bactericide.
Release tests against E. coli were also carried out showing that the silver/polyurethane achieved exerts its biocidal activity through slow release of silver nanoparticles. Two different mechanisms reported in literature were invoked to account for the biocidal action of the silver
Journal of Biomedical Nanotechnology (JBN) is a peer-reviewed multidisciplinary journal providing broad coverage in all research areas focused on the applications of nanotechnology in medicine, drug delivery systems, infectious disease, biomedical sciences, biotechnology, and all other related fields of life sciences.