@article {Zhang:2012:1550-7033:372,
title = "A CCD-Based Reader Combined Quantum Dots-Labeled Lateral Flow Strips for Ultrasensitive Quantitative Detection of Anti-HBs Antibody",
journal = "Journal of Biomedical Nanotechnology",
parent_itemid = "infobike://asp/jbn",
publishercode ="asp",
year = "2012",
volume = "8",
number = "3",
publication date ="2012-06-01T00:00:00",
pages = "372-379",
itemtype = "ARTICLE",
issn = "1550-7033",
url = "https://www.ingentaconnect.com/content/asp/jbn/2012/00000008/00000003/art00002",
doi = "doi:10.1166/jbn.2012.1401",
keyword = "HBV, LATERAL FLOW CHIP, QUANTITATIVE ANALYSIS, ANTIBODY, QUANTUM DOTS, SURFACE ANTIGEN, CCD",
author = "Zhang, Xueqing and Li, Ding and Wang, Can and Zhi, Xiao and Zhang, Chunlei and Wang, Kan and Cui, Daxiang",
abstract = "Herein we reported a CCD-based reader combined quantum dots-labeled lateral flow strips for ultrasensitive quantitative detection of anti-HBs antibody. The CdTe quantum dots were prepared, then were used to label Hepatitis B Virus surface antigen, and then were fabricated into lateral
flow strips. The as-prepared lateral flow strips were used to test different concentration of anti-HBV surface antibodies. The CCD-based reader was designed and fabricated, the quantitative analysis software was compiled, and resultant CCD-based reader system was used for quantitative analysis
of examined anti-HBs antibodies on the strips. Results showed that the quantum dots-labeled lateral flow strips could detect the anti-HBs antibody with the limitation concentration of 200 pg/mL, the CCD-based reader system could detect anti-HBs antibody with the sensitivity of 2 pg/mL. In
conclusion, the prepared CCD-based reader combined quantum dots-labeled lateral flow strips can be used for quantitative detection of anti-HBs antibody in sera with the sensitivity of 2 pg/mL, and has great potential in applications such as ultrasensitive detection of HBV antigens or antibodies,
and other tumor biomarkers in near future.",
}