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Nanomedicine: New Challenges and Opportunities in Cancer Therapy

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Abstract:

Nanomedicine contribution to cancer therapy is notoriously improving survival and quality of life of cancer patients. Currently there are several products already available on the market, and many others are in the preclinical-to clinical pipeline. Nanomedicine could bring the tools necessary to improve inherent limitations of classical pharmacotherapy. In this review, we offer a comprehensive analysis of the progress made in the design of biodegradable nanocarriers particularly adapted for the delivery of anticancer drugs, including classical low molecular weight drugs, peptides and nucleic acid based therapeutics. Furthermore, we analyze the benefits provided by these drug delivery platforms, such as improving the long-term stability, injectability, biodistribution and efficacy of anticancer drugs.

Keywords: ACTIVE TARGETING; CANCER; INTRACELLULAR DELIVERY; NANOMEDICINE; PASSIVE TARGETING

Document Type: Review Article

DOI: https://doi.org/10.1166/jbn.2008.339

Publication date: 2008-09-01

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  • Journal of Biomedical Nanotechnology (JBN) is a peer-reviewed multidisciplinary journal providing broad coverage in all research areas focused on the applications of nanotechnology in medicine, drug delivery systems, infectious disease, biomedical sciences, biotechnology, and all other related fields of life sciences.
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