Skip to main content

Micelles from Poly(ethylene glycol)–Phosphatidyl Ethanolamine Conjugates (Peg-Pe) as Pharmaceutical Nanocarriers for Poorly Soluble Drug Camptothecin

Buy Article:

$105.00 plus tax (Refund Policy)

Nanoparticulate drug carriers, polymeric micelles made from conjugates of polyethylene glycol and phosphatidylethanolamine (PEG-PE) have been successfully used for the solubilization of the poorly soluble anticancer drug camptothecin (CPT). CPT-loaded micelles had the size of ca. 15 nm, were stable upon storage, and firmly retained the incorporated drug. The cytotoxicity of CPT-loaded PEG-PE micelles in different cell culture models was significantly higher than that of the free drug. The CPT incorporated PEG-PE micelles may represent a novel development in the poorly soluble drug delivery systems.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
No Metrics


Document Type: Research Article

Publication date: 01 June 2005

More about this publication?
  • Journal of Biomedical Nanotechnology (JBN) is a peer-reviewed multidisciplinary journal providing broad coverage in all research areas focused on the applications of nanotechnology in medicine, drug delivery systems, infectious disease, biomedical sciences, biotechnology, and all other related fields of life sciences.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • Terms & Conditions
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more