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Free Content Acute Neurologic Toxicity Related to Nasal Insufflation of Crushed Oxycodone: A Case Series and Review of the Literature

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Oxycodone is a prescription semisynthetic opiate that has been at the center of an increase in prescription drug abuse. The brain toxicity of oxycodone has not been well established, particularly when the drug is not used as intended, such as nasal insufflation of crushed oxycodone pills. Three cases are presented of acute neurologic injury in patients after nasal insufflation of oxycodone and discussed potential pathogenesis, which may differ from that of other commonly abused opiates.
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Document Type: Research Article

Publication date: 2017-02-01

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  • Neurographics is the peer-reviewed, quarterly educational journal of the American Society of Neuroradiology. The journal comprises mainly articles created from select scientific exhibits at the ASNR Annual Meeting. Neurographics will also publish other high-quality submissions that are primarily educational and have a high emphasis on a pictorial approach. Articles are available free online, and a print-on-demand edition can be ordered from the Neurographics site.

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