Free Content Human Exposure to the Jet Fuel, JP-8

Authors: Tu, Raymond H.; Mitchell, Clifford S.; Kay, Gary G.; Risby, Terence H.

Source: Aviation, Space, and Environmental Medicine, Volume 75, Number 1, January 2004 , pp. 49-59(11)

Publisher: Aerospace Medical Association

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Abstract:

Tu RH, Mitchell CS, Kay GG, Risby TH. Human exposure to the jet fuel, JP-8. Aviat Space Environ Med 2004; 75:49-59.

Introduction: This study investigates anecdotal reports that have suggested adverse health effects associated with acute or chronic exposure to jet fuel. Methods: JP-8 exposure during the course of the study day was estimated using breath analysis. Health effects associated with exposure were measured using a neurocognitive testing battery and liver and kidney function tests. Results: Breath analysis provided an estimate of an individual's recent JP-8 exposure that had occurred via inhalation and dermal routes. All individuals studied on base exhaled aromatic and aliphatic hydrocarbons that are found in JP-8. The subject who showed evidence of the most exposure to JP-8 had a breath concentration of 11.5 mg · m−3 for total JP-8. This breath concentration suggested that exposure to JP-8 at an Air Guard Base is much less than exposure observed at other Air Force Bases. This reduction in exposure to JP-8 is attributed to the safety practices and standard operating procedures carried out by base personnel. The base personnel who exhibited the highest exposures to JP-8 were fuel cell workers, fuel specialists and smokers, who smoked downwind from the flightline. Discussion: Although study-day exposures appear to be much less than current guidelines, chronic exposure at these low levels appeared to affect neurocognitive functioning. JP-8-exposed individuals performed significantly poorer than a sample of non-exposed age- and education-matched individuals on 20 of 47 measures of information processing and other cognitive functions.

Keywords: exposure assessment; breath analysis; neurocognitive effects; renal and liver function

Document Type: Research article

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