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A Case-Based Approach to Evaluating Azithromycin Use and Cardiovascular Risks

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Azithromycin is a commonly prescribed macrolide antibiotic for the management of community-acquired pneumonia in the outpatient setting. Recent data have led to a growing concern of abnormal changes in cardiac electrophysiology and arrhythmias associated with its use. As azithromycin continues to be prescribed, clinicians should be aware of the new safety data and how it may affect concomitant medications or comorbid conditions in a patient. This article utilizes a case-based approach to assess azithromycin use and the risk of QT-prolongation and cardiac arrhythmias.
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Keywords: Arrhythmias; Azithromycin; CAP = Community-acquired pneumonia; Community-acquired pneumonia; ICU = Intensive care unit; IDSA = Infectious Diseases Society of America; Macrolides; Methadone; QT-prolongation; Risperidone; Torsade de pointes

Document Type: Research Article

Publication date: 2014-01-01

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  • The Consultant Pharmacist® is the official peer-reviewed journal of the American Society of Consultant Pharmacists. It is dedicated exclusively to the medication needs of the elderly in all settings, including adult day care, ambulatory care, assisted living, community, hospice, and nursing facilities. This award-winning journal is a member benefit of ASCP. Individuals who are not members and wish to receive The Consultant Pharmacist® will want to consider joining ASCP.
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